Blar i forfatter "Katsoulis, Michail"

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    • Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis 

      Bouras, Emmanouil; Karhunen, Ville; Gill, Dipender; Huang, Jian; Haycock, Philip C.; Gunter, Marc J.; Johansson, Mattias; Brennan, Paul; Key, Tim; Lewis, Sarah J.; Martin, Richard M.; Murphy, Neil; Platz, Elizabeth A.; Travis, Ruth; Yarmolinsky, James; Zuber, Verena; Martin, Paul; Katsoulis, Michail; Freisling, Heinz; Nøst, Therese Haugdahl; Schulze, Matthias B.; Dossus, Laure; Hung, Rayjean J.; Amos, Christopher I.; Ahola-Olli, Ari; Palaniswamy, Saranya; Männikkö, Minna; Auvinen, Juha; Herzig, Karl-Heinz; Keinänen-Kiukaanniemi, Sirkka; Lehtimäki, Terho; Salomaa, Veikko; Raitakari, Olli; Salmi, Marko; Jalkanen, Sirpa; Jarvelin, Marjo-Riitta; Dehghan, Abbas; Tsilidis, Konstantinos K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-11)
      Background - Epidemiological and experimental evidence has linked chronic inflammation to cancer aetiology. It is unclear whether associations for specific inflammatory biomarkers are causal or due to bias. In order to examine whether altered genetically predicted concentration of circulating cytokines are associated with cancer development, we performed a two-sample Mendelian randomisation (MR) ...

    • Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer: a Mendelian Randomization analysis using data from three large cohort studies 

      Nimptsch, Katharina; Song, Mingyang; Aleksandrova, Krasimira; Katsoulis, Michail; Freisling, Heinz; Jenab, Mazda; Gunter, Marc J.; Tsilidis, Konstantinos K.; Weiderpass, Elisabete; Bueno-De-Mesquita, Hendrik Bastiaan; Chong, Dawn Q.; Jensen, Majken K.; Wu, Chunsen; Overvad, Kim; Kühn, Tilman; Barrdahl, Myrto; Melander, Olle; Jirström, Karin; Peeters, Petra H.; Sieri, Sabina; Panico, Salvatore; Cross, Amanda J.; Riboli, Elio; van Guelpen, Bethany; Myte, Robin; Huerta, José María; Rodriguez-Barranco, Miguel; Quirós, José Ramón; Dorronsoro, Miren; Tjønneland, Anne; Olsen, Anja; Travis, Ruth; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Severi, Gianluca; Bonet, Catalina; Palli, Domenico; Janke, Jürgen; Lee, Young-Ae; Boeing, Heiner; Giovannucci, Edward L.; Ogino, Shuji; Fuchs, Charles S.; Rimm, Eric; Wu, Kana; Chan, Andrew T.; Pischon, Tobias (Journal article; Manuskript; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-05-26)
      Higher levels of circulating adiponectin have been related to lower risk of colorectal cancer in several prospective cohort studies, but it remains unclear whether this association may be causal. We aimed to improve causal inference in a Mendelian Randomization meta-analysis using nested case–control studies of the European Prospective Investigation into Cancer and Nutrition (EPIC, 623 cases, 623 ...

    • Quantification of the smoking-associated cancer risk with rate advancement periods: Meta-analysis of individual participant data from cohorts of the CHANCES consortium 

      Ordóñez-Mena, José Manuel; Schöttker, Ben; Mons, Ute; Jenab, Mazda; Freisling, Heinz; Bueno-De-Mesquita, Hendrik Bastiaan; O'Doherty, Mark G.; Scott, Angela; Kee, Frank; Stricker, Bruno H.; Hofman, Albert; de Keyser, Catherine E.; Ruiter, Rikje; Söderberg, Stefan; Jousilahti, Pekka; Kuulasmaa, Kari; Freedman, Neal D.; Wilsgaard, Tom; de Groot, Lisette C.P.G.M.; Kampman, Ellen; Håkansson, Niclas; Orsini, Nicola; Wolk, Alicja; Nilsson, Lena Maria; Tjønneland, Anne; Pająk, Andrzej; Malyutina, Sofia; Kúbinová, Růžena; Tamosiunas, Abdonas; Bobak, Martin; Katsoulis, Michail; Orfanos, Philippos; Boffetta, Paolo; Trichopoulou, Antonia; Brenner, Hermann (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-05)
      Background:<br> Smoking is the most important individual risk factor for many cancer sites but its association with breast and prostate cancer is not entirely clear. Rate advancement periods (RAPs) may enhance communication of smoking related risk to the general population. Thus, we estimated RAPs for the association of smoking exposure (smoking status, time since smoking cessation, smoking ...